CARING FOR THE PEOPLE OF NORTHEAST MICHIGAN

 

GREAT LAKES HEART CENTER OF ALPENA

 

Beta Blockers 
  • should be continued in patients undergoing surgery who are receiving beta blockers
  • patients undergoing vascular surgery who are at high cardiac risk owing to the finding of ischemia on preoperative testing.
  • patients undergoing vascular or intermediate - risk surgery in whom preoperative assessment identifies CAD (Class II).
  • patients undergoing vascular or intermediate - risk surgery who are at high cardiac risk, defined by the presence of more than 1 clinical riskfactor (Class II).
  • the usefulness of beta blockers is uncertain in patients undergoing intermediate-risk or vascular surgery, in whom one clinical risk factor is present (Class II).
  • the usefulness of beta blockers is uncertain in patients undergoing vascular surgery with no clinical risk factors and who are not currently on beta blockers (Class II).
 Beta blocker therapy should ne used with caution in patients with decompensated HF, nonischemic cardiomyopathy, or severe valvular heart disease in the absence of CHD .

Dose should be titrated to achieve a heart rate of 60-65 bpm.

Statin therapy
  • statins should be continued in patients currently taking the drug and scheduled for noncardiac surgery.
  • statin use is reasonable in patients undergoing vascular surgery (Class II).
  • statins may be considered in patients with at least 1 clinical risk factor scheduled yo undergo intermediate-risk procedures (Class II).

Calcium Channel Blockers (CCB)
There is very little data to support the use of CCB. One meta-analysis of 11 studies showed CCB reduced the incidence of ischemia and SVT. The majority of these benefits were attributable to diltiazem.
Nitroglycerin
  • The usefulness of nitrates to prevent myocardial ischemia and cardiac morbidity during surgery is unclear, particularly for patients who have required nitrate therapy to control angina.
  • Nitrates may actually lead to cardiovascular decompensationby decreasing preload.
  • Topical nitroglycerin may have uneven absorption intraoperatively, so when clinically indicated, administer nitroglycerin intravenously.
  • The venodilating and arterial dilating effects of nitroglycerin are mimicked by some anesthetic agents, so that the combination of agents can cause hypotension and myocardial ischemia.


Therefore, nitroglycerin should be used only when the hemodynamic effects of other agents being used and intravascular volume status have been considered.


Alpha-2 Agonists

Alpha-2 agonists for perioperative control of hypertension may be considered for patients with known CAD or at least 1 clinical risk factor who are undergoing surgery.